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Acetaminophen vs. ibuprofen(asteriskmag.com)
629 points by nkurz | 408 comments
An Asterisk Magazine essay by Dynomight comparing acetaminophen and ibuprofen, covering overdose risks, narrow therapeutic windows, and what doctors want patients to know.
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There is no epidemic of loneliness, but there is an epidemic of scurvy(experimental-history.com)
59 points by luu | 31 comments
An Experimental History Substack essay by Adam Mastroianni arguing there is no loneliness epidemic but there is an epidemic of scurvy.
Ozempic is changing the foods Americans buy(news.cornell.edu)
411 points by giuliomagnifico | 748 comments
Cornell Chronicle article on research finding that GLP-1 drugs like Ozempic and Wegovy are associated with reductions in Americans' grocery and food purchases.
The world is awful. The world is much better. The world can be much better(ourworldindata.org)
363 points by colonCapitalDee | 265 comments
Max Roser essay on Our World in Data arguing the world is simultaneously awful, much better than before, and capable of becoming much better.
Jake Seliger has died(marginalrevolution.com)
908 points by A_D_E_P_T | 189 comments
Alex Tabarrok's Marginal Revolution post remembering writer Jake Seliger after his death from cancer, noting his advocacy for faster drug development.
We haven't seen the worst of what gambling and prediction markets will do(derekthompson.org)
826 points by mmcclure | 576 comments
Derek Thompson essay arguing that the spread of gambling and prediction markets in America will cause worse social harm than people expect.
Why are there so many rationalist cults?(asteriskmag.com)
459 points by glenstein | 695 comments
Asterisk Magazine essay by Ozy Brennan examining why the Rationalist community tends to spawn cult-like high-demand groups.












