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Cancer vaccine for Yash, he's diagnosed with stage IV pancreatic cancer(github.com)

23 points by AsDivyansh 2 days ago | 4 comments

GitHub repository from the RNA Foundry sharing tumour sequencing data, code, and designs for a personalized mRNA cancer vaccine for a stage IV pancreatic cancer patient.

mrna-vaccinecancer-vaccinepancreatic-cancerbioinformatics

Show HN: Ramasite, a Self-Contained Laravel/Filament/SQLite CMS(github.com)

3 points by DaleFranks 1 day ago | 0 comments

GitHub repository for RamaSite, a self-contained MIT-licensed CMS built with Laravel, Filament and SQLite, largely written with Claude Code.

cmslaravelfilamentsqlite

Show HN: Write GitHub Actions in any language: Loopt(github.com)

7 points by Bnjoroge 4 days ago | 0 comments

GitHub repository for Loopt, a Rust tool that lets you write GitHub Actions workflows in languages like Rust, Python, TypeScript, and Go and compiles them to YAML.

github-actionsci-cdyamlrust

Show HN: Agents infer Lego mechanisms from sources, then animate them(github.com)

24 points by antelocnova 7 days ago | 1 comments

GitHub repository for LDraw Mecha, agent tooling that infers mechanisms from LDraw LEGO model files and animates them as Blender files.

ldrawlegoblenderai-agents

I Use Development-Driven Specs, Not Spec-Driven Development(github.com)

14 points by WaywardGeek 5 days ago | 8 comments

GitHub repository for Ensemble, an open-source book that builds an AI coding agent, which in turn helps write the next edition; README explains development-driven specs.

ai-coding-agentsdevelopment-driven-specificationsspec-driven-developmentgo

6-11X speedup running Qwen3.6 on my RTX 4090, full repo.(github.com)

10 points by AI4Science 6 hours ago | 0 comments

GitHub repository for Lightreason, a Python/CUDA project claiming LLM token-generation speedups for Qwen models on consumer GPUs, with benchmarks and a demo chat.

llm-inferencespeculative-decodingqwenrtx-4090

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Show HN: We built an open source, zero webhooks payment processor(github.com)

375 points by agreeahmed 11 months ago | 209 comments

GitHub repository for Flowglad, an open source payments and billing infrastructure that integrates without webhooks and exposes real-time feature and usage-credit state.

flowgladpaymentsbillingstripe-alternative

Show HN: PhreshOS – OS for Web Apps(github.com)

6 points by zouhirdx 1 month ago | 2 comments

GitHub repository for PhreshOS, an MIT-licensed open-source browser-based desktop system that hosts web apps as Node.js threads with built-in auth and real-time communication.

phreshosweb-desktopself-hostednodejs

Show HN: Argus- open source security platform to protect against agentic attacks(github.com)

11 points by thomasunise 20 days ago | 1 comments

GitHub repository for Argus, an open-source agentic security operations platform with an evidence graph, swarm-aware detections, governed AI agents, and an approval-gated action broker.

agentic-securitysecurity-operationsai-agentsthreat-detection

OpenLLaMA: An Open Reproduction of LLaMA(github.com)

414 points by sadiq 3 years ago | 144 comments

GitHub repository for OpenLLaMA, an Apache-2.0 licensed open reproduction of Meta's LLaMA language model, with a 200B-token preview release.

llamaopenllamalarge-language-modelsopen-source-models

Nvidia – open-source auto-ontology(github.com)

248 points by campervans 10 days ago | 116 comments

GitHub repository for NVIDIA's Auto Ontology, an Apache-2.0 Python framework for building graph-based semantic reasoning layers over data for LLM and agent workflows.

nvidiaontologyknowledge-graphtext-to-sql

Show HN: We open sourced our entire text-to-SQL product(github.com)

437 points by aazo11 2 years ago | 140 comments

GitHub repository for Dataherald, an open-sourced natural-language-to-SQL engine using LLM agents, with admin console, enterprise backend, and Slackbot services.

text-to-sqlllmdataheraldsql