22 stories tagged clinical-trials, newest first.
136 points by _Microft | 25 comments
Ars Technica article reporting Phase 3 results showing Moderna and Merck's personalized mRNA melanoma vaccine with Keytruda cut recurrence or death risk by 42%.
40 points by gone35 | 4 comments
Sijbrandij Foundation's Future of Cancer Care Today (FCCT) initiative page, on helping cancer patients access more diagnostics, treatments, and trials than one care team can track.
17 points by elo2000 | 7 comments
Vinay Prasad's Substack post arguing that Terence Tao misused a cancer drug analogy when discussing AI solving math problems without explaining mechanisms.
108 points by jajoosam | 22 comments
PopVax blog post announcing the first participants dosed in Melbourne in a Phase 1 first-in-human trial of its broadly-protective COVID-19 vaccine candidate PVX-001.
147 points by luu | 39 comments
Broad Institute news article announcing that a clinical trial of an siRNA drug candidate targeting the prion protein has begun enrolling human participants.
498 points by heydenberk | 231 comments
X post by Moderna co-founder Noubar Afeyan announcing positive Phase 3 results for intismeran autogene, an individualized mRNA neoantigen therapy for melanoma with Keytruda.
322 points by Shortness8 | 184 comments
Science magazine article reporting on a girl's undisclosed death in a Chinese gene-editing trial whose parents paid over $800k; page shows a Cloudflare check.
358 points by surprisetalk | 271 comments
A Dynomight blog essay arguing that claims Vitamin D supplements are worthless are somewhat overstated, reviewing the evidence on their effects.
331 points by giuliomagnifico | 161 comments
King's College London news article reporting that universities and hospitals repurpose existing drugs via late-stage trials at up to 90% lower cost than pharma.
413 points by andsoitis | 143 comments
Economist article reporting that a promising pancreatic cancer drug may be the first of a new class of treatments targeting a cancer master switch.
337 points by gmays | 64 comments
UC Davis Health news article reporting a study finding that the first in-utero stem cell therapy for fetal spina bifida repair is safe.
672 points by _zie | 115 comments
BBC News article reporting that Huntington's disease has been successfully treated for the first time, by health and science correspondent James Gallagher.
425 points by marc__1 | 84 comments
Rockefeller University news article on a clinical trial of an engineered CD40 agonist antibody that shrank or eliminated tumors in about half of patients.
376 points by amichail | 665 comments
MedPath news article on a randomized trial of 108 people with HIV-associated lipohypertrophy where weekly Ozempic reversed epigenetic biological age by 3.1 years.
515 points by Thomvis | 329 comments
Medscape conference news article on the first long-term comparison finding psilocybin outperformed escitalopram for moderate to severe major depressive disorder.
375 points by shoggouth | 146 comments
Times article profiling Simon Westbrook, a former Pfizer scientist who spent his redundancy money and 14 years developing an osteoarthritis treatment.
1108 points by jdkee | 140 comments
Jake Seliger's blog post announcing he is entering hospice after his squamous cell carcinoma progressed and efforts to find another clinical trial failed.
775 points by toomuchtodo | 345 comments
Bloomberg news article reporting that Gilead's twice-yearly HIV prevention shot prevented all infections in a large trial of African women.
473 points by keploy | 194 comments
Cosmos Magazine article reporting that a gene therapy restored hearing in children born with inherited deafness.
597 points by belter | 276 comments
Independent news article reporting that 18-month-old Opal Sandy, born deaf from auditory neuropathy, had her hearing restored in a world-first gene therapy trial.
723 points by theoldlove | 386 comments
Jake Seliger's blog post describing his terminal squamous cell carcinoma and arguing that FDA delays keep potentially life-saving treatments out of reach.
905 points by elorant | 278 comments
Mainichi news article on a Japanese research team's tooth regrowth medication heading to clinical trials starting July 2024.